No public access
master's thesis
REGULATION OF HIF1 ALPHA EXPRESSION IN NORMAL ANDINFLAMMATORY CHANGED TISSUE THROUGH HYPERBARIC OXYGENATION IN BALB/c MICE

Katarina Guberac (2014)
Sveučilište Josipa Jurja Strossmayera u Osijeku
Odjel za biologiju
Metadata
TitleREGULACIJA EKSPRESIJE HIF1 ALFA U NORMALNOM I UPALNO PROMJENJENOM TKIVU PUTEM HIPERBARIČNE OKSIGENACIJE KOD BALB/c MIŠEVA
AuthorKatarina Guberac
Mentor(s)Elizabeta Has Schon (thesis advisor)
Martina Mihalj (thesis advisor)
Abstract
Upalna bolest crijeva (engl. Inflammatory Bowel Disease, IBD) sastoji se od nekoliko upalnihbolesti probavnog trakta od kojih su najčešće Crohnova bolest i ulcerozni kolitis. Međuvišestrukim modelima mišjeg kolitisa, jedan od najčešće korištenih uključuje primjenudekstran natrij sulfata (engl. Dextran Sodium Sulphate, DSS) koji uzrokuje bolest vrlo sličnuljudskom ulceroznom kolitisu. BALB/c miševima inducira se upala kolona te sehiperbaričnom oksigenacijom (HBO2) djeluje na smanjenje simptoma bolesti i težine kolitisakao i na smanjenje ekspresije HIF-1 alfa
KeywordsHIF-1 alpha BALB/c mice dextran sodium sulphate colitis hyperbaric oxygenation
Parallel title (English)REGULATION OF HIF1 ALPHA EXPRESSION IN NORMAL ANDINFLAMMATORY CHANGED TISSUE THROUGH HYPERBARIC OXYGENATION IN BALB/c MICE
Committee MembersElizabeta Has Schon (committee chairperson)
Martina Mihalj (committee member)
Ivna Štolfa Čamagajevac (committee member)
GranterSveučilište Josipa Jurja Strossmayera u Osijeku
Odjel za biologiju
PlaceOsijek
StateCroatia
Scientific field, discipline, subdisciplineNATURAL SCIENCES
Biology
Study programme typeuniversity
Study levelgraduate
Study programmeMaster of Science Graduate University Study Programme in Biology; specializations in: Master of Biology
Study specializationMaster of Biology
Academic title abbreviationmag.biol.
Genremaster's thesis
Language Croatian
Defense date2014-10-30
Parallel abstract (English)
Inflammatory Bowel Disease comprises of several inflammatory diseases of the gastrointestinal tract, most frequently Crohn' s disease and ulcerative colitis. Among multiple models of murine colitis, one of the most commonly used includes dextran sodium sulphate(DSS) treatment which causes disease similar to human ulcerative colitis. Colitis was induced in BALB/c mice and the hyperbaric oxygenation reduced the symptoms of desease andseverity of colitis as well the reduced expression of HIF-1 alpha
Parallel keywords (Croatian)HIF-1 alfa BALB/c miševi dekstran natrij sulfat (DSS) kolitis hiperbaričnaoksigenacija (HBO2)
Resource typetext
Access conditionNo public access
Terms of usehttp://rightsstatements.org/vocab/InC/1.0/
URN:NBNhttps://urn.nsk.hr/urn:nbn:hr:181:619697
CommitterVesna Radman Meic