| Abstract | CILJ ISTRAŽIVANJA:
Cilj ovoga istraživanja je utvrditi učestalost većeg FIGO stadija i stupnja raka endometrija, te veću učestalost komorbiditeta od šećerne bolesti i hipertenzije u ispitanica starije životne dobi operiranih u KBC-u Split od raka endometrija. Podatci koji će se analizirati su dob, paritet, FIGO stadij, stupanj, te postojeće bolesti kao što su šećerna bolest i hipertenzija.
USTROJ ISTRAŽIVANJA:
Retrospektivno smo analizirali podatke 71 ispitanice koje su operirane u Klinici za ženske bolesti i porode tijekom 2011. godine.
MJESTO ISTRAŽIVANJA:
Istraživanje je provedeno u Klinici za ženske bolesti i porode Kliničkog bolničkog centra u Splitu, Split, Hrvatska.
SUDIONICI:
U istraživanje smo uključili pacijentice s dijagnozom raka endometrija. Sve pacijentice su bile operirane u Klinici za ženske bolesti i porode KBC Split tijekom 2011. godine zbog raka endometrija i potvrđenim pozitivnim PHD nalazom raka endometrija.Pacijentice su bile podjeljene u dvije skupine po dobi. Jedna skupina su bili pacijentice dobi od 65 i manje godina, a druga skupina su bile pacijentice starije od 65 godina.
GLAVNE MJERE ISHODA:
Usporedba odnosa promatranih parametara ovisno o dobnim skupinama ispitanica. Glavni parametri su FIGO stadij, stupanj raka, menarha, vrsta karcinoma i komorbiditet.
REZULTATI:
Najveći broj ispitanica bio je u dobnoj skupini od 56. do 65. godine, 32,4 % što se pokazalo statistički značajno (χ2= 14,563, df=4, P=0,005). Od ispitanica oboljelih od raka endometrija 88,7 % bile su u postmenopauzi, što se pokazalo statistički značajno (χ2=42,606, df=1, P<0,001). Nije postojala statistički značajna razlika u prisutnosti stupnja raka endometrija i različitih dobnih skupina ispitanica u istraživanom uzorku(χ2 test=0,167; df=1; P=0,682) Ispitanice u dobi >65 nisu značajno učestalije imale imale FIGO stadij ≥II (χ2 test=0,474; df=1; P=0,491).
ZAKLJUČAK:
U našem istraživanju dokazali smo da se rak endometrija najčešće se dijagnosticira u dobi od 56. do 65. godine. Većina ispitanica je u vrijeme dijagnosticiranja raka bila u postmenopauzi, a najčešća dijagnosticirana vrsta raka bio je endometroidni adenokarcinom. Invazivni oblici raka nisu povezani sa starijom dobi (>65 godina). |
| Abstract (english) | OBJECTIVE:
The aim of this study was to determine the higher incidence of FIGO stage and grade of endometrial cancer and higher incidence of diabetes and hypertension in elderly patients treated in Clinical hospital centre in Split from endometrial cancer. The data that were analyzed were age, parity, FIGO stage, grade, and preexisting diseases such as diabetes and hypertension.
DESIGN:
We retrospectively analyzed data from 71 patients who underwent surgery at the Department of obstetrics and gynecology in 2011 year.
SETTINGS:
The study was conducted at the Department of gynecology and obstetrics at Clinical hospital center in Split, Split, Croatia.
PARTICIPANTS:
The study included patients diagnosed with endometrial cancer. All patients were operated at the Department of obstetrics and gynecology in Clinical hospital centre Split in 2011 year due to endometrial cancer and positive finding of cancer with PHD. Patients were divided into two groups by age. One group of patients were 65 years old or less, and the other group were patients older than 65 years.
MAIN OUTCOME MEASURES:
Comparison of correlation between the observed parameters depending on the age groups of patients. The main parameters were FIGO stage, grade of cancer, menarche, type of cancer and comorbidity.
RESULTS:
Most of the patients were in the age group of 56-65 years what was proved to be statistically significant (χ2 = 14.563, df = 4, P = 0.005). Patients suffering from endometrial cancer were in 88.7 % cases in postmenopause, what was proved to be statistically significant (χ2 = 42.606, df = 1, P <0.001). There was no statistically significant difference in the presence of grade of endometrial cancer and older age group of women in the studied sample (χ2 test = 0.167, df = 1, P = 0.682) . Patients aged> 65 didn’t have significantly more often FIGO stage ≥ II of endometrial cancer (χ2 test = 0.474, df = 1, P = 0.491).
CONCLUSION:
In our study we proved that endometrial cancer is usually diagnosed between the ages of 56-65 years. Most of the patients at the time of diagnosis of cancer were in postmenopause. Most frequently diagnosed type of cancer was endometrial adenocarcinoma. Invasive cancers were not associated with older age (> 65 years). |
