Objective: The main objective of this study was to analyze total influenza morbidity, categorize it by age, to show mortality and vaccination against influenza as well as the analysis of the vaccination by risk groups. Methods: In this retrospective study, publicly available data published in Croatian health statistics yearbook and the Report of vaccination implementation of Croatian institute of public health was analyzed, in the time period from 2014. to 2019. Descriptive statistics was used for data analysis. Results: In the time period from 2014. to 2019. largest number of inhabitants infected from the influenza in Republic of Croatia was recorded in the influenza season 2014./2015., with 78 234 infected. In the season 2015./2016. there was least infected inhabitants, 21 138. Influenza incidence is highest in school and preschool age children (5- 14 years old) and highest incidence was recorded in 2014./2015. season when 3528,1 of 100 000 children was affected with influenza. Lowest influenza incidence was in persons in age of 65 years old or more and in season 2015./2016. only 139,2 of 100 000 elderly got infected. In 2015., the lowest number of reported deaths from influenza was recorded, 5 deaths; while the highest number was recorded in 2016., with 27 deaths. Season 2018./2019. achieved highest vaccination coverage, with a population of 323 085. Lowest vaccination coverage was recorded in 2015./2016. season with 250 826 inhabitants. There are risk groups that vaccination is recommended and those are elderly/retirees, chronic patients and health workers. From these, the most vaccinated are retired people, 67% vaccinated in the influenza season 2018./2019. Highest vaccination coverage of chronic patients was recorded in 2017./2018., but falls in 2018./2019. with total of 25%. Health workers maintain a constant of 3%. Largest number of distributed vaccines was in the season 2018./2019. and 98% of those doses were used. Conclusion: In the Republic of Croatia there has been a trend of increasing vaccination coverage against influenza. The highest vaccination rate is in persons over 65 years old. Despite the good vaccination coverage of older persons, the targeted coverage of 75% was not achieved. Children are least vaccinated and therefore risk group. It is necessary to achieve high vaccination coverage against influenza. That would reduce morbidity and complications, as well as reduce „excess deaths“ in elderly people. The nurse plays an important role in prevention, diagnosis and treatment of influenza. Also, it is necessary to ensure continous informing and education and raise awareness about influenza prevention and vaccination.