prikaz prve stranice dokumenta Uloga tumor supresorskih gena CDH1 I MLH1 u sporadičnim karcinomima dojke
Access restricted to students and staff of home institution
undergraduate thesis
Uloga tumor supresorskih gena CDH1 I MLH1 u sporadičnim karcinomima dojke
Zagreb: University of Zagreb, Faculty of Food Technology and Biotechnology, 2014. urn:nbn:hr:159:156523
Ujčić, Silvia
University of Zagreb
Faculty of Food Technology and Biotechnology
Department of Biochemical Engineering
Laboratory for Biology and Microbial Genetics

Cite this document

Ujčić, S. (2014). Uloga tumor supresorskih gena CDH1 I MLH1 u sporadičnim karcinomima dojke (Undergraduate thesis). Zagreb: University of Zagreb, Faculty of Food Technology and Biotechnology. Retrieved from https://urn.nsk.hr/urn:nbn:hr:159:156523

Ujčić, Silvia. "Uloga tumor supresorskih gena CDH1 I MLH1 u sporadičnim karcinomima dojke." Undergraduate thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, 2014. https://urn.nsk.hr/urn:nbn:hr:159:156523

Ujčić, Silvia. "Uloga tumor supresorskih gena CDH1 I MLH1 u sporadičnim karcinomima dojke." Undergraduate thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, 2014. https://urn.nsk.hr/urn:nbn:hr:159:156523

Ujčić, S. (2014). 'Uloga tumor supresorskih gena CDH1 I MLH1 u sporadičnim karcinomima dojke', Undergraduate thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, accessed 19 April 2024, https://urn.nsk.hr/urn:nbn:hr:159:156523

Ujčić S. Uloga tumor supresorskih gena CDH1 I MLH1 u sporadičnim karcinomima dojke [Undergraduate thesis]. Zagreb: University of Zagreb, Faculty of Food Technology and Biotechnology; 2014 [cited 2024 April 19] Available at: https://urn.nsk.hr/urn:nbn:hr:159:156523

S. Ujčić, "Uloga tumor supresorskih gena CDH1 I MLH1 u sporadičnim karcinomima dojke", Undergraduate thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, Zagreb, 2014. Available at: https://urn.nsk.hr/urn:nbn:hr:159:156523

Please login to the repository to save this object to your list.
Metadata
TitleUloga tumor supresorskih gena CDH1 I MLH1 u sporadičnim karcinomima dojke
Title (english)Role of tumor suppressor genes CDH1 AND MLH1 in sporadic breast cancer
AuthorSilvia Ujčić
MentorReno Hrašćan (mentor)
GranterUniversity of Zagreb
Faculty of Food Technology and Biotechnology
(Department of Biochemical Engineering)
(Laboratory for Biology and Microbial Genetics)
Zagreb
Defense date and country2014-09-11, Croatia
Scientific / art field,
discipline and subdiscipline		BIOTECHNICAL SCIENCES
Biotechnology
Abstract
Rak dojke jedan je od vodećih uzročnika smrti u žena. Rezultat je to uzajamnog djelovanja genetskih i okolišnih čimbenika koji ,karcinom, posljedično svrstavaju u kompleksnu heterogenu bolest. Karcinom se smatra bolešću gena jer se nastanak i progresija tumora razvijaju stupnjevitim promjenama na razini gena što se očituje kao abnormalan i nesvrhovit rast stanica. Skupina gena koja priječi tu zloćudnu preobrazbu na različitim razinama su tumor supresorski geni koji svojim menanizmom popravka imaju spopsobnost vratiti tumorsku stanicu u normalne okvire rasta. Njihov gubitak ili inaktivacija u stanici rezultira razvitkom tumora. U ovom radu pobliže je razjašnjena uloga dvaju tumor supresorskih gena CDH1 i MLH1 ključnih u razvitku sporadičnog karcinoma dojke koji nije pod utjecajem nasljedne obiteljske anamneze.
Abstract (english)
Breast cancer is one of the leading causes of women's death. It's the result of interaction between genetic and environmental factors which consequently classify the cancer as a complex heterogeneous disease. Cancer is considered a disease of genes, because the occurrence and progression of tumor develops by a gradual change on the gene which results as abnormal and unpurposeful cell growth. Group of genes which prevents the malignant transformation at different levels are the tumor suppressor genes which have the ability to restore the tumor cell growth in normal proportions. Their loss or inactivation in the cells, results with tumor evolvement. In this study is further clarified the role of two tumor suppressor genes CDH1 and MLH1 which are key in the evolvement of sporadic breast cancer that is not influenced by familial history.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:159:156523
Study programmeTitle: Biotechnology
Study programme type: university
Study level: undergraduate
Academic / professional title: sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) inženjer/inženjerka biotehnologije (sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) inženjer/inženjerka biotehnologije)
Type of resourceText
File originBorn digital
Access conditionsAccess restricted to students and staff of home institution
Terms of useLicence In copyright icon
RepositoryRepository of the Faculty of Food Technology and Biotechnology
Created on2017-04-27 10:41:21

(©) Nacionalna i sveučilišna knjižnica u Zagrebu 2015. Sva prava pridržana. | Hrvatske bratske zajednice 4 p.p. 550, 10000 Zagreb, Hrvatska Tel. ++ 385 1 616-4040
OIB: 84838770814 | IBAN: HR66 2340 0091 1000 1008 1, Porezni broj (PDV identifikacijski broj) - VAT Number: HR84838770814
Prijava u repozitorij