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master's thesis
Razvoj UPLC metode za odjeljivanje enantiomera tetramizola
Zagreb: University of Zagreb, Faculty of Pharmacy and Biochemistry, 2016. urn:nbn:hr:163:361503
Poljak, Tea
University of Zagreb
Faculty of Pharmacy and Biochemistry

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Poljak, T. (2016). Razvoj UPLC metode za odjeljivanje enantiomera tetramizola (Master's thesis). Zagreb: University of Zagreb, Faculty of Pharmacy and Biochemistry. Retrieved from https://urn.nsk.hr/urn:nbn:hr:163:361503

Poljak, Tea. "Razvoj UPLC metode za odjeljivanje enantiomera tetramizola." Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, 2016. https://urn.nsk.hr/urn:nbn:hr:163:361503

Poljak, Tea. "Razvoj UPLC metode za odjeljivanje enantiomera tetramizola." Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, 2016. https://urn.nsk.hr/urn:nbn:hr:163:361503

Poljak, T. (2016). 'Razvoj UPLC metode za odjeljivanje enantiomera tetramizola', Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, accessed 25 April 2024, https://urn.nsk.hr/urn:nbn:hr:163:361503

Poljak T. Razvoj UPLC metode za odjeljivanje enantiomera tetramizola [Master's thesis]. Zagreb: University of Zagreb, Faculty of Pharmacy and Biochemistry; 2016 [cited 2024 April 25] Available at: https://urn.nsk.hr/urn:nbn:hr:163:361503

T. Poljak, "Razvoj UPLC metode za odjeljivanje enantiomera tetramizola", Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, Zagreb, 2016. Available at: https://urn.nsk.hr/urn:nbn:hr:163:361503

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Metadata
TitleRazvoj UPLC metode za odjeljivanje enantiomera tetramizola
Title (english)The development of a UPLC method for separating tetramisole enantiomers
AuthorTea Poljak
MentorBiserka Cetina Čižmek (mentor)
Committee memberBiserka Cetina Čižmek (predsjednik povjerenstva)
Committee memberBiljana Nigović (član povjerenstva)
GranterUniversity of Zagreb
Faculty of Pharmacy and Biochemistry
Zagreb
Defense date and country2016-11-14, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Pharmacy
Pharmacy
Abstract
U ovom diplomskom radu uspješno je razvijena metoda za odjeljivanje enantiomera tetramizola. Mijenjanjem uvjeta metoda ispitane su četiri različite kolone, kiralne i ne-kiralne. Uspješno je razvijena metoda na ACQUITY UPC2 Trefoil AMY1 (2,1 x 150 mm, 2,5 μm) i Chiralpak IC-3 (2,1 x 100 mm, 3 μm) koloni. Za odjeljivanje enantiomera tetramizola na ACQUITY UPC2 Trefoil AMY1 koloni potrebno je 4,0 min, dok je za njihovo odjeljivanje na Chiralpak IC-3 koloni potrebno 5,0 min. Metoda je validirana na obje kolone.
Abstract (english)
In this study, a UPLC method for separating tetramisole enantiomers was successfully developed. By changing method conditions, four columns were tested, both chiral and non-chiral. The method was successfully developed using ACQUITY UPC2 Trefoil AMY1 (2.1 x 150 mm, 2.5 μm) and Chiralpak IC-3 (2.1 x 100 mm, 3 μm) columns. The estimated time for separating dexamisole and levamisole using the ACQUITY UPC2 Trefoil AMY1 column amounts to 4.0 minutes, while 5.0 minutes are needed to separate the two enantiomers when using the Chilarpak IC-3 column. The method was validated with regard to both columns.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:163:361503
Study programmeTitle: Pharmacy
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: magistar/magistra farmacije (magistar/magistra farmacije)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
RepositoryRepository of Faculty of Pharmacy and Biochemistry University of Zagreb
Created on2017-09-13 12:20:54

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