Utjecaj uvođenja deriviranog fibrinogena na financijsko poslovanje laboratorija

Prkić, Martina

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master's thesis

Utjecaj uvođenja deriviranog fibrinogena na financijsko poslovanje laboratorija

Zagreb: University of Zagreb, Faculty of Pharmacy and Biochemistry, 2018. urn:nbn:hr:163:419109

Prkić, Martina

University of Zagreb
Faculty of Pharmacy and Biochemistry
Department of medical biochemistry and haematology

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APA 6th Edition

Prkić, M. (2018). Utjecaj uvođenja deriviranog fibrinogena na financijsko poslovanje laboratorija (Master's thesis). Zagreb: University of Zagreb, Faculty of Pharmacy and Biochemistry. Retrieved from https://urn.nsk.hr/urn:nbn:hr:163:419109

MLA 8th Edition

Prkić, Martina. "Utjecaj uvođenja deriviranog fibrinogena na financijsko poslovanje laboratorija." Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, 2018. https://urn.nsk.hr/urn:nbn:hr:163:419109

Chicago 17th Edition

Harvard

Prkić, M. (2018). 'Utjecaj uvođenja deriviranog fibrinogena na financijsko poslovanje laboratorija', Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, accessed 22 January 2025, https://urn.nsk.hr/urn:nbn:hr:163:419109

Vancouver

Prkić M. Utjecaj uvođenja deriviranog fibrinogena na financijsko poslovanje laboratorija [Master's thesis]. Zagreb: University of Zagreb, Faculty of Pharmacy and Biochemistry; 2018 [cited 2025 January 22] Available at: https://urn.nsk.hr/urn:nbn:hr:163:419109

IEEE

M. Prkić, "Utjecaj uvođenja deriviranog fibrinogena na financijsko poslovanje laboratorija", Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, Zagreb, 2018. Available at: https://urn.nsk.hr/urn:nbn:hr:163:419109

Cite this item: https://urn.nsk.hr/urn:nbn:hr:163:419109

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Title	Utjecaj uvođenja deriviranog fibrinogena na financijsko poslovanje laboratorija
Title (english)	How Using Derived Fibrinogen Method Affects Financial Performance of a Laboratory
Author	Martina Prkić
Mentor	Dunja Rogić (mentor)
Committee member	Dunja Rogić (predsjednik povjerenstva)
Committee member	Nada Vrkić (član povjerenstva)
Committee member	Desiree Coen Herak (član povjerenstva)
Granter	University of Zagreb Faculty of Pharmacy and Biochemistry (Department of medical biochemistry and haematology) Zagreb
Defense date and country	2018-12-17, Croatia
Scientific / art field, discipline and subdiscipline	BIOMEDICINE AND HEALTHCARE Pharmacy Medical Biochemistry
Abstract	Izračunavanje koncentracije fibrinogena iz krivulje kojom je analizirano protrombinsko vrijeme kod hospitaliziranih pacijenata jedna je od mjera uštede koju koriste brojni laboratoriji. U ovom diplomskom radu obrađeni su podatci izdanih pretraga fibrinogena i deriviranog fibrinogena u redovnom i hitnom laboratoriju Kliničkog zavoda za laboratorijsku dijagnostiku KBC Zagreb unutar prvih devet mjeseci 2018. godine. Ukupna ušteda laboratorija zamjenom eksperimentalne metode deriviranim fibrinogenom u tom razdoblju iznosi 107.897,36 kn. Budući da je pretraga deriviranog fibrinogena uvedena kao mjera štednje 2014. godine, tijekom te četiri godine ušteđeno je oko 575.000,00 kn. Ako se ispravno postave kriteriji, dolazi do velike uštede financijskih sredstava, ali isto tako i uštede vremena koje je potrebno za izdavanje koagulacijskog nalaza što moţe biti od osobite važnosti u hitnim stanjima. Međutim, potrebno je imati na umu kako ova metoda nije međulaboratorijski usporediva te se ne bi smjela koristiti kod vanjskih pacijenata. Također, zbog velikog broja nedostataka koji se pojavljuju uglavnom u patološkim stanjima, koja su i češća kod hospitaliziranih bolesnika, bilo je potrebno jako pažljivo odrediti kriterije korištenja ove metode kako bi razina kvalitete rezultata koagulacijskih pretraga ostala očuvana unatoč značajnom smanjenju financijskog opterećenja laboratorija. Ipak, u određenim stanjima, kao što je diseminirana intravaskularna koagulacija, dobiveni rezultati mogu biti čak i točniji od rezultata izmjerenih modificiranom Claussovom tehnikom. Isto tako, treba uzeti u obzir i plato područja sigmoidne krivulje koja se primjećuju kod pretjerano niskih i visokih vrijednosti u plazmi. Ipak, uzevši u obzir sva ograničenja koja ova metoda donosi, moguće je i uz stroge uvjete postići značajnu uštedu od oko tri četvrtine resursa u odnosu na izvođenje ove pretrage modificiranom Claussovom metodom što postaje vrlo relevantno u smanjenju troškova laboratorija i moţe činiti integralni dio uštede većih bolničkih centara.
Abstract (english)	Calculating fibrinogen concentration from data availalble in prothrombine time curve in samples from hospitalized patients is one of the measures of savings that a lot of laboratories use. This paper covers the data of released results of fibrinogen and derived fibrinogen in routine and emergency laboratories at Clinical Hospital Centre Zagreb in the first nine months of 2018. The total savings obtained by switching from experimental Clauss essay method to prothrombin time derived fibrinogen are 107, 897.36 kn. Because this method of measurment started in 2014, during this four years the savings are around 575,000.00 kn. If the criteria are set up correctly, a large amount of money can be saved, and also a lot of time for issuing the coagulation report which is particularly important in emergency situations. But this method isn't comparable between laboratories and it shouldn't be used with external patients. Also, because of a great deal of defects that appear mostly in phatological state that are also more common among hospitalized patients, the criteria for using this method had to be chosen very carefully, so that the quality level of coagulation reports stays maintained, inspite of a significant reduction in the finantial burden of the laboratory. What's more, in certain phatological states, such as disseminated intravascular coagulation, the results may be even more correct than the results given by the modified Clauus technique. Of course, the plateau areas at the beginning and the end of the sigmoid curve in plasma measurments need to be taken into account. After taking in consideration all of the restrictions this method carries and providing it's being carried out under strict conditions, it's possible to achieve significant savings of about three quarters of resources. That fact becomes very relevant in reducing the laboratory expenses and it can become an integral part of savings for bigger hospital centers.
Keywords
Keywords (english)
Language	croatian
URN:NBN	urn:nbn:hr:163:419109
Study programme	Title: Medical biochemistry Study programme type: university Study level: integrated undergraduate and graduate Academic / professional title: magistar/magistra medicinske biokemije (magistar/magistra medicinske biokemije)
Type of resource	Text
File origin	Born digital
Access conditions	Open access
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Repository	Repository of Faculty of Pharmacy and Biochemistry University of Zagreb
Created on	2020-02-14 08:31:59