Identifikacija proteina iz smjese metodom spektrometrije mase

Zajec, Marina

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master's thesis

Identifikacija proteina iz smjese metodom spektrometrije mase

Zagreb: University of Zagreb, Faculty of Pharmacy and Biochemistry, 2015. urn:nbn:hr:163:384962

Zajec, Marina

University of Zagreb
Faculty of Pharmacy and Biochemistry
Department of biochemistry and molecular biology

Cite this document

APA 6th Edition

Zajec, M. (2015). Identifikacija proteina iz smjese metodom spektrometrije mase (Master's thesis). Zagreb: University of Zagreb, Faculty of Pharmacy and Biochemistry. Retrieved from https://urn.nsk.hr/urn:nbn:hr:163:384962

MLA 8th Edition

Zajec, Marina. "Identifikacija proteina iz smjese metodom spektrometrije mase." Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, 2015. https://urn.nsk.hr/urn:nbn:hr:163:384962

Chicago 17th Edition

Zajec, Marina. "Identifikacija proteina iz smjese metodom spektrometrije mase." Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, 2015. https://urn.nsk.hr/urn:nbn:hr:163:384962

Harvard

Zajec, M. (2015). 'Identifikacija proteina iz smjese metodom spektrometrije mase', Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, accessed 24 January 2025, https://urn.nsk.hr/urn:nbn:hr:163:384962

Vancouver

Zajec M. Identifikacija proteina iz smjese metodom spektrometrije mase [Master's thesis]. Zagreb: University of Zagreb, Faculty of Pharmacy and Biochemistry; 2015 [cited 2025 January 24] Available at: https://urn.nsk.hr/urn:nbn:hr:163:384962

IEEE

M. Zajec, "Identifikacija proteina iz smjese metodom spektrometrije mase", Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, Zagreb, 2015. Available at: https://urn.nsk.hr/urn:nbn:hr:163:384962

Cite this item: https://urn.nsk.hr/urn:nbn:hr:163:384962

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Metadata

Title	Identifikacija proteina iz smjese metodom spektrometrije mase
Title (english)	Identification of proteins from mixture by mass spectrometry method
Author	Marina Zajec
Mentor	Olga Gornik (mentor)
Committee member	Olga Gornik
Committee member	Sandra Šupraha Goreta
Committee member	Ana Mornar Turk
Granter	University of Zagreb Faculty of Pharmacy and Biochemistry (Department of biochemistry and molecular biology) Zagreb
Defense date and country	2015-09-30, Croatia
Scientific / art field, discipline and subdiscipline	BIOMEDICINE AND HEALTHCARE Pharmacy Pharmacy
Abstract	Proteini su jedne od najvažnijih makromolekula u ljudskome tijelu. Kontroliraju mehanizme koji dovode do različitih bolesti i zbog toga su sveprisutna tema istraživanja. Tema ovog rada je identifikacija proteina iz smjese metodom spektrometrije mase. U istraživanju je korišten MALDI-Q-TOF spektrometar mase. Uvođenje MALDI ionskog izvora spojenog sa tandem Q-TOF analizatorom je osiguralo sredstva za dobivanje pouzdanih MS i MS/MS podataka. Cilj je dobiti podatke o masama peptida i fragmenata koji su korisni za identifikaciju proteina i sastava smjese uz pomoć proteinskih baza sekvenci. U istraživanju je kao uzorak korištena ljudska plazma i identificiran albumin kao najobilniji protein.
Abstract (english)	Proteins are one of the most important macromolecules in the human body. They control the mechanisms causing various diseases and that makes them an ubiquitous research theme. Topic of this thesis is protein identification from mixture using mass spectrometry. MALDI-Q-TOF mass spectrometer was used in the research. Introduction of a MALDI ion source coupled to a tandem Q-TOF analyser has provided means to obtain reliable MS and MS/MS data. Aim is to acquire data about peptide masses and fragments useful for identification of proteins and mixture composition with the help of protein databases. Sample being used was human plasma and albumin was identified as the most abundant protein.
Keywords
Keywords (english)
Language	croatian
URN:NBN	urn:nbn:hr:163:384962
Study programme	Title: Pharmacy Study programme type: university Study level: integrated undergraduate and graduate Academic / professional title: magistar/magistra farmacije (magistar/magistra farmacije)
Type of resource	Text
File origin	Born digital
Access conditions	Access restricted to students and staff of home institution
Terms of use
Repository	Repository of Faculty of Pharmacy and Biochemistry University of Zagreb
Created on	2016-02-22 10:25:39