Određivanje antioksidacijskog djelovanja odabranih vrsta roda Salvia L.

Škugor, Doris

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master's thesis

Određivanje antioksidacijskog djelovanja odabranih vrsta roda Salvia L.

Zagreb: University of Zagreb, Faculty of Pharmacy and Biochemistry, 2020. urn:nbn:hr:163:121402

Škugor, Doris

University of Zagreb
Faculty of Pharmacy and Biochemistry
Department of pharmacognosy

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APA 6th Edition

Škugor, D. (2020). Određivanje antioksidacijskog djelovanja odabranih vrsta roda Salvia L. (Master's thesis). Zagreb: University of Zagreb, Faculty of Pharmacy and Biochemistry. Retrieved from https://urn.nsk.hr/urn:nbn:hr:163:121402

MLA 8th Edition

Škugor, Doris. "Određivanje antioksidacijskog djelovanja odabranih vrsta roda Salvia L.." Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, 2020. https://urn.nsk.hr/urn:nbn:hr:163:121402

Chicago 17th Edition

Harvard

Škugor, D. (2020). 'Određivanje antioksidacijskog djelovanja odabranih vrsta roda Salvia L.', Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, accessed 24 January 2025, https://urn.nsk.hr/urn:nbn:hr:163:121402

Vancouver

Škugor D. Određivanje antioksidacijskog djelovanja odabranih vrsta roda Salvia L. [Master's thesis]. Zagreb: University of Zagreb, Faculty of Pharmacy and Biochemistry; 2020 [cited 2025 January 24] Available at: https://urn.nsk.hr/urn:nbn:hr:163:121402

IEEE

D. Škugor, "Određivanje antioksidacijskog djelovanja odabranih vrsta roda Salvia L.", Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, Zagreb, 2020. Available at: https://urn.nsk.hr/urn:nbn:hr:163:121402

Cite this item: https://urn.nsk.hr/urn:nbn:hr:163:121402

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Title	Određivanje antioksidacijskog djelovanja odabranih vrsta roda Salvia L.
Title (english)	Determination of antioxidant activities of selected Salvia species
Author	Doris Škugor
Mentor	Sanda Vladimir-Knežević (mentor)
Committee member	Sanda Vladimir-Knežević (predsjednik povjerenstva)
Committee member	Maja Bival Štefan (član povjerenstva)
Committee member	Renata Jurišić Grubešić (član povjerenstva)
Granter	University of Zagreb Faculty of Pharmacy and Biochemistry (Department of pharmacognosy) Zagreb
Defense date and country	2020-09-29, Croatia
Scientific / art field, discipline and subdiscipline	BIOMEDICINE AND HEALTHCARE Pharmacy Pharmacy
Abstract	U okviru ovog diplomskog rada istraženi su prisutnost i antioksidacijski učinak fenolnih spojeva u metanolnim i etanolnim ekstraktima listova odabranih vrsta roda Salvia s područja Hrvatske (S. brachyodon, S. fruticosa, S.glutinosa, S. nemorosa, S. officinalis, S. pratensis, S. sclarea i S. verticillata). Primjenom metode tankoslojne kromatografije dokazana je prisutnost ružmarinske kiseline i luteolin-7-O-glukozida u listovima svih uzoraka. Kvercitrin je prisutan samo u vrsti S. verticillata, a rutin u vrstama S. brachyodon, S. fruticosa i S. officinalis. Antioksidacijski učinak etanolnih ekstrakata ispitan je pomoću tri spektrofotometrijske metode u usporedbi s troloksom i EDTA. Utvrđena je sposobnost hvatanja DPPH radikala (IC50: 3,88-7,93 μg/mL), redukcije iona željeza(III) ( IC50: 9,43- 18,36 μg/mL) te keliranja iona željeza(II) ( IC50: 163,55-1592,53μg/mL). Dobiveni rezultati pokazuju da istraživane biljne vrste sadrže flavonoide i fenolne kiseline koji doprinose njihovim antioksidacijskim učincima.
Abstract (english)	The presence of phenolic compounds and their antioxidative effect in methanolic and ethanolic leaf extracts of selected species of the Salvia genus from Croatia (S. brachyodon, S. fruticosa, S.glutinosa, S. nemorosa, S. officinalis, S. pratensis, S. sclarea and S. verticillata) were studied in this diploma thesis. The presence of rosmarinic acid and luteolin-7-O-glucoside was detected by thin-layer chromatography in all leaf samples. Quercitrin was present only in the S. verticillata extract and rutin was detected in leaf extracts of S. brachyodon, S. fruticosa and S. officinalis. The antioxidative effects of ethanolic extracts were determined by using three spectrophotometric methods in comparison to trolox and EDTA. The abilities of scavenging DPPH radical (IC50: 3.88- 7.93 μg/mL), reduce ferric ions (IC50: 9.43-18.36 μg/mL) and chelate ferrous ions were determined. The obtained results have shown that the studied plant species contain flavonoids and phenolic acids which contribute to their antioxidative effects.
Keywords
Keywords (english)
Language	croatian
URN:NBN	urn:nbn:hr:163:121402
Study programme	Title: Pharmacy Study programme type: university Study level: integrated undergraduate and graduate Academic / professional title: magistar/magistra farmacije (magistar/magistra farmacije)
Type of resource	Text
File origin	Born digital
Access conditions	Open access Embargo expiration date: 2022-09-29
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Repository	Repository of Faculty of Pharmacy and Biochemistry University of Zagreb
Created on	2022-08-26 13:18:58