Ultrazvučna ekstrakcija polifenolnih spojeva iz
 vrste Satureja montana L. upotrebom (2-
 hidroksipropil)-β-ciklodekstrina i glicerola

Margetić, Helena

prikaz prve stranice dokumenta Ultrazvučna ekstrakcija polifenolnih spojeva iz vrste Satureja montana L. upotrebom (2- hidroksipropil)-β-ciklodekstrina i glicerola

Embargo period 2025-04-03

master's thesis

Ultrazvučna ekstrakcija polifenolnih spojeva iz vrste Satureja montana L. upotrebom (2- hidroksipropil)-β-ciklodekstrina i glicerola

Zagreb: University of Zagreb, Faculty of Pharmacy and Biochemistry, 2023. urn:nbn:hr:163:856284

Margetić, Helena

University of Zagreb
Faculty of Pharmacy and Biochemistry
Department of pharmacognosy

Cite this document

APA 6th Edition

Margetić, H. (2023). Ultrazvučna ekstrakcija polifenolnih spojeva iz vrste Satureja montana L. upotrebom (2- hidroksipropil)-β-ciklodekstrina i glicerola (Master's thesis). Zagreb: University of Zagreb, Faculty of Pharmacy and Biochemistry. Retrieved from https://urn.nsk.hr/urn:nbn:hr:163:856284

MLA 8th Edition

Margetić, Helena. "Ultrazvučna ekstrakcija polifenolnih spojeva iz vrste Satureja montana L. upotrebom (2- hidroksipropil)-β-ciklodekstrina i glicerola." Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, 2023. https://urn.nsk.hr/urn:nbn:hr:163:856284

Chicago 17th Edition

Harvard

Margetić, H. (2023). 'Ultrazvučna ekstrakcija polifenolnih spojeva iz vrste Satureja montana L. upotrebom (2- hidroksipropil)-β-ciklodekstrina i glicerola', Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, accessed 17 January 2025, https://urn.nsk.hr/urn:nbn:hr:163:856284

Vancouver

Margetić H. Ultrazvučna ekstrakcija polifenolnih spojeva iz vrste Satureja montana L. upotrebom (2- hidroksipropil)-β-ciklodekstrina i glicerola [Master's thesis]. Zagreb: University of Zagreb, Faculty of Pharmacy and Biochemistry; 2023 [cited 2025 January 17] Available at: https://urn.nsk.hr/urn:nbn:hr:163:856284

IEEE

H. Margetić, "Ultrazvučna ekstrakcija polifenolnih spojeva iz vrste Satureja montana L. upotrebom (2- hidroksipropil)-β-ciklodekstrina i glicerola", Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, Zagreb, 2023. Available at: https://urn.nsk.hr/urn:nbn:hr:163:856284

Cite this item: https://urn.nsk.hr/urn:nbn:hr:163:856284

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Title	Ultrazvučna ekstrakcija polifenolnih spojeva iz vrste Satureja montana L. upotrebom (2- hidroksipropil)-β-ciklodekstrina i glicerola
Title (english)	Ultrasonic extraction of polyphenolic compounds from Satureja montana L. using (2- hydroxypropyl)-β-cyclodextrin and glycerol
Author	Helena Margetić
Mentor	Marijana Zovko Končić (mentor)
Committee member	Marijana Zovko Končić (predsjednik povjerenstva)
Committee member	Maja Bival Štefan (član povjerenstva)
Committee member	Lidija Bach-Rojecky (član povjerenstva)
Granter	University of Zagreb Faculty of Pharmacy and Biochemistry (Department of pharmacognosy) Zagreb
Defense date and country	2023-03-04, Croatia
Scientific / art field, discipline and subdiscipline	BIOMEDICINE AND HEALTHCARE Pharmacy Pharmacy
Abstract	Satureja montana L. (Lamiaceae) sadrži raznolike bioaktivne spojeve, a najviše njih spada u skupinu polifenolnih spojeva. Zadatak rada bio je ultrazvučnom ekstrakcijom prirediti ekstrakte nadzemih dijelova vrste S. montana uz upotrebu glicerola i (2-hidroksipropil)-β-ciklodekstrina (HP-β-CD) bogate fenolnim spojevima: ukupnim polifenolima, fenolnim kiselinama, flavonoidima i ružmarinskom kiselinom. Od 20 ispitivanih uzoraka E10 se istaknuo kao ekstrakt kod kojeg se optimizacijom uvjeta postiglo najbolje ekstrakcijsko iskorištenje. Sadržaj ukupnih polifenola u tom ekstraktu bio je 5506,42 μg/mL, ukupnih fenolnih kiselina 3514,44 μg/mL, ukupnih flavonoida 645,72 μg/mL a koncentracija ružmarinske kiseline 822,70 μg/mL. Radom je dokazano kako ekstrakcijski medij voda/glicerol/ HP-β-CD izvrsno ekstrakcijsko sredstvo za polifenolne spojeve vrste S. montana.
Abstract (english)	Satureja montana L. (Lamiaceae) contains a variety of bioactive compounds, and most of them belong to the group of polyphenolic compounds. The task of the work was to prepare extracts of the aerial parts of S. montana with the use of glycerol and (2-hydroxypropyl)-β-cyclodextrin (HP-β-CD) rich in phenolic compounds: total polyphenols, phenolic acids, flavonoids and rosmarinic acid. Out of 20 tested samples, E10 was the extract in which the optimization of conditions lead to the highest extraction yield. The content of total polyphenols in this extract was 5506.42 μg/mL, total phenolic acids was 3514.44 μg/mL, total flavonoids was 645.72 μg/mL and the concentration of rosemarinic acid was 822.70 μg/mL. This work has proven that the water/glycerol/ HP-β-CD is an excellent extraction medium for polyphenolic compounds of the S. montana.
Keywords
Keywords (english)
Language	croatian
URN:NBN	urn:nbn:hr:163:856284
Study programme	Title: Pharmacy Study programme type: university Study level: integrated undergraduate and graduate Academic / professional title: magistar/magistra farmacije (magistar/magistra farmacije)
Type of resource	Text
File origin	Born digital
Access conditions	Embargoed access Embargo expiration date: 2025-04-03
Terms of use
Repository	Repository of Faculty of Pharmacy and Biochemistry University of Zagreb
Created on	2023-04-13 12:39:42