Fitokemijska karakterizacija vrsta roda Globularia L. koje rastu na području Republike Hrvatske

Musić, Karolina

prikaz prve stranice dokumenta Fitokemijska karakterizacija vrsta roda Globularia L. koje rastu na području Republike Hrvatske

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master's thesis

Fitokemijska karakterizacija vrsta roda Globularia L. koje rastu na području Republike Hrvatske

Zagreb: University of Zagreb, Faculty of Pharmacy and Biochemistry, 2015. urn:nbn:hr:163:933518

Musić, Karolina

University of Zagreb
Faculty of Pharmacy and Biochemistry
Department of pharmaceutical botany

Cite this document

APA 6th Edition

Musić, K. (2015). Fitokemijska karakterizacija vrsta roda Globularia L. koje rastu na području Republike Hrvatske (Master's thesis). Zagreb: University of Zagreb, Faculty of Pharmacy and Biochemistry. Retrieved from https://urn.nsk.hr/urn:nbn:hr:163:933518

MLA 8th Edition

Musić, Karolina. "Fitokemijska karakterizacija vrsta roda Globularia L. koje rastu na području Republike Hrvatske." Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, 2015. https://urn.nsk.hr/urn:nbn:hr:163:933518

Chicago 17th Edition

Harvard

Musić, K. (2015). 'Fitokemijska karakterizacija vrsta roda Globularia L. koje rastu na području Republike Hrvatske', Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, accessed 15 January 2025, https://urn.nsk.hr/urn:nbn:hr:163:933518

Vancouver

Musić K. Fitokemijska karakterizacija vrsta roda Globularia L. koje rastu na području Republike Hrvatske [Master's thesis]. Zagreb: University of Zagreb, Faculty of Pharmacy and Biochemistry; 2015 [cited 2025 January 15] Available at: https://urn.nsk.hr/urn:nbn:hr:163:933518

IEEE

K. Musić, "Fitokemijska karakterizacija vrsta roda Globularia L. koje rastu na području Republike Hrvatske", Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, Zagreb, 2015. Available at: https://urn.nsk.hr/urn:nbn:hr:163:933518

Cite this item: https://urn.nsk.hr/urn:nbn:hr:163:933518

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Metadata

Title	Fitokemijska karakterizacija vrsta roda Globularia L. koje rastu na području Republike Hrvatske
Title (english)	Phytochemical characterization of species from the genus Globularia L. growing on Croatian territory
Author	Karolina Musić
Mentor	Kroata Hazler Pilepić (mentor)
Committee member	Kroata Hazler Pilepić
Committee member	Željan Maleš
Committee member	Renata Jurišić Grubešić
Granter	University of Zagreb Faculty of Pharmacy and Biochemistry (Department of pharmaceutical botany) Zagreb
Defense date and country	2015-07-10, Croatia
Scientific / art field, discipline and subdiscipline	BIOMEDICINE AND HEALTHCARE Pharmacy Pharmacy
Abstract	U okviru ovog rada provedena su fitokemijska ispitivanja na vrstama roda Globularia L. koje rastu na području Hrvatske. Provedene fitokemijske reakcije u epruveti na metanolnim ekstraktima i praškastom biljnom materijalu vrsta Globularia alypum, Globularia cordifolia, Globularia meridionalis i Globularia punctata utvrdile su prisutnost flavonoida, trjeslovina, fenolnih kiselina, iridoida, triterpena, antocijana u tragovima te manjih količina saponina. Metodom tankoslojne kromatografije detektirani su flavonoidi apigenin, apigenin 7-O-glukozid te luteolin 7-O-glukozid, a kod vrste G. punctata prisutan je i rutin. Također je dokazano da od svih ispitivanih vrsta G. punctata sadrži najveći broj flavonoida. Tankoslojnom kromatografijom detektirani su i iridoidi, i to katalpol kod vrsta G. alypum i G. punctata, aukubin kod vrsta G. cordifolia i G. meridionalis te asperulozid kod vrsta G. cordifolia, G. meridionalis i G. punctata. Tankoslojnom kromatografijom utvrđena je prisutnost derivata kavene i klorogenske kiseline te verbaskozida u svim ispitivanim vrstama roda Globularia. Ovakva preliminarna istraživanja bitna su jer otkrivaju ljekoviti potencijal nedovoljno istraženih biljnih vrsta koje rastu na području Hrvatske. Vrsta G. alypum otprije je poznata u narodnoj medicini, između ostalog, kao hipoglikemik, laksativ, purgativ i kolagog.
Abstract (english)	Within this study phytochemical tests were carried out on species of the Globularia L. genus growing on Croatian territory. Phytochemical reactions conducted in test tubes on methanolic extracts and powdered plant material of Globularia alypum, Globularia cordifolia, Globularia meridionalis and Globularia punctata species identified the presence of flavonoids, tannins, phenolic acids, iridoids, triterpenes, anthocyanins in traces and minor amounts of saponins. Thin layer chromatography detected the apigenin, apigenin 7-O-glucoside and luteolin 7-O-glucoside flavonoids. Rutin was detected within G. punctata species. G. punctata was also proven to contain the highest amount of flavonoids among all tested species. Thin layer chromatography detected also iridoids,catalpol within G. alypum and G. punctata species, aucubin within G. cordifolia and G. meridionalis species and asperuloside within G. cordifolia, G. meridionalis and G. punctata species. Thin layer chromatography determined the presence of caffeic and chlorogenic acid derivatives and verbascoside in all tested species from the Globularia genus. This type of preliminary research is important because they reveal the medicinal potential of under-researched plant species that grow on Croatian territory. The species G. alypum has been known in folk medicine, among other things, as a hypoglycemic agent, laxative, purgative and cholagogue.
Keywords
Keywords (english)
Language	croatian
URN:NBN	urn:nbn:hr:163:933518
Study programme	Title: Pharmacy Study programme type: university Study level: integrated undergraduate and graduate Academic / professional title: magistar/magistra farmacije (magistar/magistra farmacije)
Type of resource	Text
File origin	Born digital
Access conditions	Access restricted to students and staff of home institution
Terms of use
Repository	Repository of Faculty of Pharmacy and Biochemistry University of Zagreb
Created on	2016-01-20 12:27:35