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undergraduate thesis
Mehanizmi nastanka multiple skleroze
Zagreb: University of Zagreb, Faculty of Science, 2023. urn:nbn:hr:217:342359
Balić, Lea
University of Zagreb
Faculty of Science
Department of Biology

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Balić, L. (2023). Mehanizmi nastanka multiple skleroze (Undergraduate thesis). Zagreb: University of Zagreb, Faculty of Science. Retrieved from https://urn.nsk.hr/urn:nbn:hr:217:342359

Balić, Lea. "Mehanizmi nastanka multiple skleroze." Undergraduate thesis, University of Zagreb, Faculty of Science, 2023. https://urn.nsk.hr/urn:nbn:hr:217:342359

Balić, Lea. "Mehanizmi nastanka multiple skleroze." Undergraduate thesis, University of Zagreb, Faculty of Science, 2023. https://urn.nsk.hr/urn:nbn:hr:217:342359

Balić, L. (2023). 'Mehanizmi nastanka multiple skleroze', Undergraduate thesis, University of Zagreb, Faculty of Science, accessed 17 January 2025, https://urn.nsk.hr/urn:nbn:hr:217:342359

Balić L. Mehanizmi nastanka multiple skleroze [Undergraduate thesis]. Zagreb: University of Zagreb, Faculty of Science; 2023 [cited 2025 January 17] Available at: https://urn.nsk.hr/urn:nbn:hr:217:342359

L. Balić, "Mehanizmi nastanka multiple skleroze", Undergraduate thesis, University of Zagreb, Faculty of Science, Zagreb, 2023. Available at: https://urn.nsk.hr/urn:nbn:hr:217:342359

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Metadata
TitleMehanizmi nastanka multiple skleroze
Title (english)Mechanisms of multiple sclerosis origin
AuthorLea Balić
MentorPetra Korać (mentor)
GranterUniversity of Zagreb
Faculty of Science
(Department of Biology)
Zagreb
Defense date and country2023-09-19, Croatia
Scientific / art field,
discipline and subdiscipline		NATURAL SCIENCES
Biology
Abstract
Multipla skleroza je kronična autoimuna upalna bolest središnjeg živčanog sustava koju karakterizira prisutnost plakova ili lezija u tkivu središnjeg živčanog sustava. Lezije nastaju zbog demijelinizacije i degeneracije aksona, procesa koji je posljedica autoimune upalne reakcije. Bolest se manifestira kroz niz neuroloških simptoma, a razvoj bolesti ovisi o tipu multiple skleroze od kojeg pacijent boluje. Zašto točno nastaje autoimuni odgovor još nije posve razjašnjeno, no dio odgovora vjerojatno je povezan s molekulskom mimikrijom između antigena podrijetla od patogena i komponenti mijelinskog ovoja neurona. Identificirani su mnogi faktori rizika, uključujući infekciju Epstein-Barrovim virusom, varijante gena HLA, izloženost sunčevoj svjetlosti i prehrambene navike.
Abstract (english)
Multiple sclerosis is a chronic autoimmune disease of the central nervous system which is characterized by the presence of plaques or lesions in the tissue of the central nervous system. Lesions are formed as a result of demyelination and degeneration of axons, a process which is the consequence of an autoimmune inflammatory reaction. The disease is manifested through a range of neurological symptoms, and the development of the disease is dependent on the type of multiple sclerosis which the patient is presenting. Exactly why the autoimmune reaction is initiated is still unclear, however, a part of the answer may lay in the molecular mimicry between an antigen originating from a pathogen and the components of the myelin sheath of neurons. Many risk factors have been identified, including Epstein-Barr virus infection, variants of HLA genes, sunlight exposure and dietary habits
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:217:342359
Study programmeTitle: Molecular Biology
Study programme type: university
Study level: undergraduate
Academic / professional title: sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) molekularne biologije (sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) molekularne biologije)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
RepositoryRepository of the Faculty of Science
Created on2023-09-20 12:34:52

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