Signalni putevi u karcinogenezi tumora

Mateševac, Josipa

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undergraduate thesis

Signalni putevi u karcinogenezi tumora

Zagreb: University of Zagreb, Faculty of Science, 2017. urn:nbn:hr:217:845526

Mateševac, Josipa

University of Zagreb
Faculty of Science
Department of Biology

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APA 6th Edition

Mateševac, J. (2017). Signalni putevi u karcinogenezi tumora (Undergraduate thesis). Zagreb: University of Zagreb, Faculty of Science. Retrieved from https://urn.nsk.hr/urn:nbn:hr:217:845526

MLA 8th Edition

Mateševac, Josipa. "Signalni putevi u karcinogenezi tumora." Undergraduate thesis, University of Zagreb, Faculty of Science, 2017. https://urn.nsk.hr/urn:nbn:hr:217:845526

Chicago 17th Edition

Mateševac, Josipa. "Signalni putevi u karcinogenezi tumora." Undergraduate thesis, University of Zagreb, Faculty of Science, 2017. https://urn.nsk.hr/urn:nbn:hr:217:845526

Harvard

Mateševac, J. (2017). 'Signalni putevi u karcinogenezi tumora', Undergraduate thesis, University of Zagreb, Faculty of Science, accessed 26 January 2025, https://urn.nsk.hr/urn:nbn:hr:217:845526

Vancouver

Mateševac J. Signalni putevi u karcinogenezi tumora [Undergraduate thesis]. Zagreb: University of Zagreb, Faculty of Science; 2017 [cited 2025 January 26] Available at: https://urn.nsk.hr/urn:nbn:hr:217:845526

IEEE

J. Mateševac, "Signalni putevi u karcinogenezi tumora", Undergraduate thesis, University of Zagreb, Faculty of Science, Zagreb, 2017. Available at: https://urn.nsk.hr/urn:nbn:hr:217:845526

Cite this item: https://urn.nsk.hr/urn:nbn:hr:217:845526

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Metadata

Title	Signalni putevi u karcinogenezi tumora
Title (english)	Signal pathways in tumor carcinogenesis
Author	Josipa Mateševac
Mentor	Nada Oršolić (mentor)
Granter	University of Zagreb Faculty of Science (Department of Biology) Zagreb
Defense date and country	2017-09-12, Croatia
Scientific / art field, discipline and subdiscipline	NATURAL SCIENCES Biology
Abstract	Karcinogeneza je kompleksan proces koji uključuje mnoge signalne puteve. Pogreške u aktivaciji pojedinog puta koje dovode do prekomjerne razine ekspresije ključnog proteina tog signalnog puta predmet su kontinuiranih znanstvenih istraživanja. Ovaj seminar daje pregled najvažnijih signalnih puteva u karcinogenezi tumora i načina ciljanog djelovanja na njihove ključne komponente radi liječenja. Mnogi putevi mogu imati imati poticajući učinak na karcinogenezu, međutim ovisno o staničnom kontekstu otkriveno je kako mogu i suprimirati inicijaciju tumora. Kemoprevencija sintetskim i prirodnim spojevima jedna je od mjera sprječavanja nastanka tumora. Liječenje ciljanim terapijama u kojima bi se kao meta odabirali pojedini ključni proteini uključenih signalnih puteva zahtijeva daljnja istraživanja. Cilj je pronaći metode koje bi dovele do inihibicije rasta ili umiranja malignih stanica, bez štetnog utjecaja na zdrave stanice organizma.
Abstract (english)	Carcinogenesis is a complex precess involving many signaling pathways. Activation dysregulation of a distinctive pathway that leads to aberrant expression level or overexpression of a crutial protein in said signal pathway are a subject of continuous scientific research. This seminar gives an overview of the most important signal pathways in tumor carcinogenesis and a way of targeted action on key components for the purpose of treatment. Many pathways have a positive effect on carcinogenesis, however, depending on cellular context, it has been discovered a tumor supression also exists. Chemoprevention by synthetic and natural compounds is a form of tumor prevention. Treatment by target therapies that select crucial proteins of activated signal pathways demands futher research. The goal is to find methods that inhibit growth or lead to malignant cell death without affecting the organism's healthy cells.
Keywords
Keywords (english)
Language	croatian
URN:NBN	urn:nbn:hr:217:845526
Study programme	Title: Molecular Biology Study programme type: university Study level: undergraduate Academic / professional title: sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) molekularne biologije (sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) molekularne biologije)
Type of resource	Text
File origin	Born digital
Access conditions	Open access
Terms of use
Repository	Repository of the Faculty of Science
Created on	2017-09-19 08:08:21