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undergraduate thesis
Signalni putevi u karcinogenezi tumora
Zagreb: University of Zagreb, Faculty of Science, 2017. urn:nbn:hr:217:845526
Mateševac, Josipa
University of Zagreb
Faculty of Science
Department of Biology

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Mateševac, J. (2017). Signalni putevi u karcinogenezi tumora (Undergraduate thesis). Zagreb: University of Zagreb, Faculty of Science. Retrieved from https://urn.nsk.hr/urn:nbn:hr:217:845526

Mateševac, Josipa. "Signalni putevi u karcinogenezi tumora." Undergraduate thesis, University of Zagreb, Faculty of Science, 2017. https://urn.nsk.hr/urn:nbn:hr:217:845526

Mateševac, Josipa. "Signalni putevi u karcinogenezi tumora." Undergraduate thesis, University of Zagreb, Faculty of Science, 2017. https://urn.nsk.hr/urn:nbn:hr:217:845526

Mateševac, J. (2017). 'Signalni putevi u karcinogenezi tumora', Undergraduate thesis, University of Zagreb, Faculty of Science, accessed 16 April 2024, https://urn.nsk.hr/urn:nbn:hr:217:845526

Mateševac J. Signalni putevi u karcinogenezi tumora [Undergraduate thesis]. Zagreb: University of Zagreb, Faculty of Science; 2017 [cited 2024 April 16] Available at: https://urn.nsk.hr/urn:nbn:hr:217:845526

J. Mateševac, "Signalni putevi u karcinogenezi tumora", Undergraduate thesis, University of Zagreb, Faculty of Science, Zagreb, 2017. Available at: https://urn.nsk.hr/urn:nbn:hr:217:845526

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Metadata
TitleSignalni putevi u karcinogenezi tumora
Title (english)Signal pathways in tumor carcinogenesis
AuthorJosipa Mateševac
MentorNada Oršolić (mentor)
GranterUniversity of Zagreb
Faculty of Science
(Department of Biology)
Zagreb
Defense date and country2017-09-12, Croatia
Scientific / art field,
discipline and subdiscipline		NATURAL SCIENCES
Biology
Abstract
Karcinogeneza je kompleksan proces koji uključuje mnoge signalne puteve. Pogreške u aktivaciji pojedinog puta koje dovode do prekomjerne razine ekspresije ključnog proteina tog signalnog puta predmet su kontinuiranih znanstvenih istraživanja. Ovaj seminar daje pregled najvažnijih signalnih puteva u karcinogenezi tumora i načina ciljanog djelovanja na njihove ključne komponente radi liječenja. Mnogi putevi mogu imati imati poticajući učinak na karcinogenezu, međutim ovisno o staničnom kontekstu otkriveno je kako mogu i suprimirati inicijaciju tumora. Kemoprevencija sintetskim i prirodnim spojevima jedna je od mjera sprječavanja nastanka tumora. Liječenje ciljanim terapijama u kojima bi se kao meta odabirali pojedini ključni proteini uključenih signalnih puteva zahtijeva daljnja istraživanja. Cilj je pronaći metode koje bi dovele do inihibicije rasta ili umiranja malignih stanica, bez štetnog utjecaja na zdrave stanice organizma.
Abstract (english)
Carcinogenesis is a complex precess involving many signaling pathways. Activation dysregulation of a distinctive pathway that leads to aberrant expression level or overexpression of a crutial protein in said signal pathway are a subject of continuous scientific research. This seminar gives an overview of the most important signal pathways in tumor carcinogenesis and a way of targeted action on key components for the purpose of treatment. Many pathways have a positive effect on carcinogenesis, however, depending on cellular context, it has been discovered a tumor supression also exists. Chemoprevention by synthetic and natural compounds is a form of tumor prevention. Treatment by target therapies that select crucial proteins of activated signal pathways demands futher research. The goal is to find methods that inhibit growth or lead to malignant cell death without affecting the organism's healthy cells.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:217:845526
Study programmeTitle: Molecular Biology
Study programme type: university
Study level: undergraduate
Academic / professional title: sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) molekularne biologije (sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) molekularne biologije)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
RepositoryRepository of the Faculty of Science
Created on2017-09-19 08:08:21

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