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master's thesis
Uloga antikoagulantne terapije u oralnoj krurgiji
Zagreb: University of Zagreb, School of Dental Medicine, 2018. urn:nbn:hr:127:236149
Pap, Ana
University of Zagreb
School of Dental Medicine
Department of Oral Surgery

Cite this document

Pap, A. (2018). Uloga antikoagulantne terapije u oralnoj krurgiji (Master's thesis). Zagreb: University of Zagreb, School of Dental Medicine. Retrieved from https://urn.nsk.hr/urn:nbn:hr:127:236149

Pap, Ana. "Uloga antikoagulantne terapije u oralnoj krurgiji." Master's thesis, University of Zagreb, School of Dental Medicine, 2018. https://urn.nsk.hr/urn:nbn:hr:127:236149

Pap, Ana. "Uloga antikoagulantne terapije u oralnoj krurgiji." Master's thesis, University of Zagreb, School of Dental Medicine, 2018. https://urn.nsk.hr/urn:nbn:hr:127:236149

Pap, A. (2018). 'Uloga antikoagulantne terapije u oralnoj krurgiji', Master's thesis, University of Zagreb, School of Dental Medicine, accessed 18 April 2024, https://urn.nsk.hr/urn:nbn:hr:127:236149

Pap A. Uloga antikoagulantne terapije u oralnoj krurgiji [Master's thesis]. Zagreb: University of Zagreb, School of Dental Medicine; 2018 [cited 2024 April 18] Available at: https://urn.nsk.hr/urn:nbn:hr:127:236149

A. Pap, "Uloga antikoagulantne terapije u oralnoj krurgiji", Master's thesis, University of Zagreb, School of Dental Medicine, Zagreb, 2018. Available at: https://urn.nsk.hr/urn:nbn:hr:127:236149

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Metadata
TitleUloga antikoagulantne terapije u oralnoj krurgiji
Title (english)The role of anticoagulation therapy in oral surgery
AuthorAna Pap
MentorAna Kotarac Knežević (mentor)
Committee memberAna Kotarac Knežević (predsjednik povjerenstva)
Committee memberMarko Granić (član povjerenstva)
Committee memberBožana Lončar Brzak (član povjerenstva)
GranterUniversity of Zagreb
School of Dental Medicine
(Department of Oral Surgery)
Zagreb
Defense date and country2018-09-19, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Dental Medicine
Oral Surgery
Abstract
Antikoagulantni su lijekovi kao terapijsko i preventivno sredstvo indicirani u velikom broju cerebrovaskularnih i kardiovaskularnih bolesti. Razlikujemo antikoagulantne i antitrombocitne lijekove. Antikoagulantni lijekovi utječu na fazu koagulacije i kaskadne reakcije, a razlikujemo one koji se primjenjuju oralno (derivati kumarina od kojih je najpoznatiji varfarin i novi antikoagulantni lijekovi dabigatran, rivaroksaban, apiksaban) i one koji se primjenjuju parenteralno (nefrakcionirani heparin, heparin niske molekularne težine, inhibitori trombina). Antitrombocitni lijekovi sprečavaju fazu agregacije trombocita, a najpoznatiji su acetilsalicilna kiselina i klopidogrel. Danas literatura ne preporučuje prekidanje terapije, čak ni dualne terapije za većinu dentalnih zahvata jer se smatra da to povećava rizik od tromboemboličkih komplikacija koji nadmašuje rizik od krvarenja. Postoperativno krvarenje koje se javlja nije fatalno i može se zaustaviti lokalnim mjerama hemostaze.
Abstract (english)
Anticoagulant drugs are prescribed as a therapeutic and preventative agent in a large number of cerebrovascular and cardiovascular diseases. We distinguish anticoagulant and antithrombotic drugs. Anticoagulant drugs affect the coagulation phase and the cascade reaction, and we distinguish those administered orally (coumarin derivatives, of which the most common is warfarin, and new anticoagulant drugs dabigatran, rivaroxaban, and apixaban) from those administered parenterally (unfractionated heparin, low molecular weight heparin, thrombin inhibitors). Antithrombotic drugs prevent the platelet aggregation phase, and the most known are acetylsalicylic acid and clopidogrel. Nowadays, scholarly literature does not recommend discontinuation of therapy, even of a dual one, for most dental procedures, as it is believed that it increases the risk of thromboembolic complications, which exceeds the risk of bleeding. Postoperative bleeding that occurs is not fatal and can be stopped by local hemostasis measures.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:127:236149
Study programmeTitle: dental medicine
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: doktor/doktorica dentalne medicine (doktor/doktorica dentalne medicine)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence Attribution-NonCommercial 3.0 Unported (CC BY-NC 3.0) icon
RepositoryUniversity of Zagreb School of Dental Medicine Repository
Created on2019-01-08 10:54:49

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