Preserving the health of periodontal tissues is the basis of fixed prosthodontic rehabilitation. Preparation of the edge of the prosthetic crown and its' placement next to the soft tissues represents a great challenge for every dentist. The relationship between gingiva and prosthesis can be monitored by respecting the biological width. Biologically oriented preparation technique is a tangential preparation which enables the “interaction” between the soft tissues and the prosthetic crown in such a way that the soft tissue forms and adapts to the new output profile of the restoration. Clinically there are no overhangs, but a new cement-enamel junction is created. The main clinical difference between subgingival and supragingival preparation is that the edge of the supragingival preparation is clearly defined, while in subgingival preparation it is placed at different levels within the gingival sulcus, without compromising the biological width. Therefore, it can be said that the biologically oriented tooth preparation technique is a minimally invasive preparation that can offer long-term stability of soft tissues and satisfactory clinical and aesthetic results. After many years of research, it has been concluded that the poor response of the periodontium occurs as a consequence of bad marginal fit of fixed prosthodontics. This technique is used in periodontally healthy teeth, remodeling of the gingival architecture, dental veneer therapy, and in implant prosthodontic rehabilitation. Further efforts are needed in order to bring the vertical preparation closer to the horizontal one in everyday practice