Non-Hodgkin lymphoma is a cancer that starts in the lymphatic system, the part of our immune system that protects us from diseases and infections. The lymphatic system consists of lymphatic tissue and lymphatic vessels that transport and collect the lymph that contains white blood cells called lymphocytes. In non-Hodgkin's lymphomas, the affected lymphocytes begin to multiply in an abnormal way and begin to collect in certain parts of the lymphatic system, such as the lymph nodes. The affected lymphocytes lose their infection-fighting properties making the immune system vulnerable. The most common symptom of non-Hodgkin lymphoma is a painless swelling in a lymph node, usually in the neck, armpit or groin. If the signs or symptoms suggest that the patient might have lymphoma, a complete medical history is made and physical examination is performed, followed by a series of diagnostic tests. A biopsy of enlarged lymph nodes or organs is needed to determine whether lymphoma exists. The treatment of the aggressive type of lymphoma usually includes a combination of chemotherapy, radiation or immunotherapy. Treatment decisions are based on the type of NHL, its staging and degree of the disease and comorbidities associated with the patient. Significant events in the life of a patient, such as lymphoma diagnosis is especially challenging for the nurses who take care for them. Nurses are responsible not only for meeting their basic human needs, but also for educating them, which is not that simple given that patients come from different ethnic and socio-economic backgrounds, and have different priorities in the healthcare process itself. Patients need psychological support and they need to be listened to regarding their disease-related fears. The aim of this paper is to describe in detail the importance of the quality health care, family support and medical staff support, especially nurses´ support in patients with non-Hodgkin lymphoma.