Communication is one of the basic human needs. We communicate constantly, whether we want it or not, consciously or unconsciously. Good communication is the foundation of any successful relationship and it is a skill that envolves throughout a lifetime. Even when people stop speaking, they do not cease to communicate, because their bodies are constantly sending information about themselves. Body language goes a long way in leaving a powerful impression on people we come across in our daily life. These signals may indicate the current emotional state of the speaker, but, depending on different cultures, they can also be misunderstood. Therefore, understanding non-verbal communication should be a key to effective communication. Gestures are an important part of our body language. Not only can they be used to complement and support what is being spoken, sometimes, they can act as the primary tool of communicating what we think, and do that more effectively than even words. Our hands play a significant role in communication throughout history. These hand gestures are the spontaneous creations of individual speaker, unique and personal. This paper presents communicational development throughout history and examines the role of hand gestures in non-verbal communication. Additionally, it examines a close connection our hands have with our brain by practicing Mudras.