Forensic facial reconstruction of deceased is important for identification of unknown persons in forensic cases when other methods did not make a positive identification of the deceased but it can also be a useful tool in a presentation of archaeological and anthropological research. The aim of this study was to reconstruct the possible appearance of St. Nicolosa Bursa, a Christian saint. The mummified remains of the saint were scanned with MSCT device (Multi-slice computed tomography) Siemens 16 with a spatial resolution of 30lp/mm and 16 rows of detectors. The 2D image thickness was 1 mm while the reconstructed 3D layers were 3 mm thick. The MSCT images were used to develop skull model which was 3D printed and used for facial reconstruction. The facial appearance recovery was accomplished using the Manchester method of the facial reconstruction by the progressive layering of clay on the ABS model according to the anthropometric data, specific for sex, age, and ancestry. The clay model was used to create the mould from which a realistic gypsum sculpture was made. When the model was compared to the photographs of the mummified remains and the MSCT scans of the Saint, it showed to be consistent with all facial traits that could be considered. Unfortunately, additional data for reconstruction and methodology validation were not available due to the preservation degree of soft tissue remains as well as the lack of pictorial or written sources about the appearance of the Saint. However, this research showed, that although the facial reconstruction is always only an approximation of the actual person’s appearance, this was the only way to find out the appearance of the saint. Present study enabled us to conduct the first reconstruction the appearance of the Christian Saint from the mummified remains and establish compatibility of characteristics of facial features of the mummified remains and the reconstruction.