Motivation is a psychological process caused by instinct and provides direction and determination in the actions of each person, towards achieving the desired goal. Work motivation should provoke in every employee a desire to improve and perform work tasks in the best possible way, in other words, motivation is an inner desire to invest effort in work activities. Many theories have been proposed that seek to explain human motivation, and each contemporary theory contributes a unique perspective with potentially new insights and distinct implications for practice and future research. All contemporary theories include a concept associated with beliefs about one’s own competence which, depending on the theory, is defined as expected success, self-efficacy, or self-confidence. The most common mentions of motivation theory in the literature are expected value theory, attribution theory, socio-cognitive theory, goal setting theory, and self-determination theory. Nurses face several difficulties in their work such as overload due to lack of resources, unstable image of nursing, demotivation at work and withdrawal from work. Such problems have a serious negative outcome on the success of nurse and can have significant consequences for the patient. Motivation and its factors are effective management tools that attract, retain and improve the work of nurses. The aim of this paper is to examine the motivation of nurses/technicians and the presence of motivation in the workplace. A total of 70 respondents participated in the research and it was conducted through a survey questionnaire and a Multidimensional scale of business motivation. The results prove that interpersonal relationships are the most important motivating factor for as many as 43% of respondents and that most respondents invest effort in the workplace because they feel proud of themselves, because they personally consider it important to invest effort in the work they do and because is investing effort in a business that works in accordance with their personal values.