This final paper aims to present the religion of Islam to compare it with Christianity and to compare Islam and Christianity in prayer. Islam is a great world religion that, like Christianity, believes in one God. The greatest prophet in Islam is Muhammad who is the one who founded the religion of Islam. Islam means peace, purity, obedience, and submission. Today it is the second-largest religion in the world. The goal of Islam is to follow the instructions of the holy book and to fulfill the gift of life according to it. The Qur'an mentions Jesus, who is a highly esteemed prophet for them, and mentions Mary, who for them is one of the greatest women in the world. In this paper we can learn more about the teachings of God and man in Islam, also, we can pay attention to the social and ethical principles of Islam in which we learn about the family life of Muslims, their state associated with religion, and the culture and customs of religion. Islam and Christianity are two large but different religions. Both religions believe in one God, but Christianity believes in the Holy Trinity which Islam denies. In Christianity, we believe that Jesus is God, and in Islam Jesus is only one of the prophets. Their interpretation of the revelation is different, for Muslim’s revelation is the greatest act that happened according to Muhammad, and for Christians, the culmination of the revelation is in Christ. We can also find a lot of differences in the issue of human rights. Prayer is a conversation with God, and it has an internal structure in every religion. For Christians, the most glorious prayer is one in which we ask that God's will be done. Christian prayer a day does not last long, while Muslims are required to pray five times a day to maintain a spiritual relationship with God.