Cervical intraepithelial neoplasia is premalignant lesion of the uterine cervix, that is a result of HPV infection. The standard screening test for the detection of premalignant and malignant neoplasms is cervical cytology via PAPA smear. Colposcopy is non invasive, and biopsy is an invasive diagnostic method that visualises changes on the cervix. Cervical conization procedures (laser conization, LLETZ, cold knife conization) are exscisional procedures that remove the cervical lesion as well as provide samples for further diagnostic analyses. Ablative therapeutic procedures (cryotherapy, laser ablation, cold coagulation, diathermy) are used for destruction of the cervical lesion, therefore these procedures are exclusively for therapeutic purposes. Croatian association of gynecologists and obstetritians established guidelines for diagnosis and treatment of CIN based on the findings of the world expert organizations, which systematically present principles and procedures in diagnosing and treating premalignant cervical lesions. The standardized treatment achieved through these guidelines and algorithms is very helpful to the specialists in making everyday decisions, however it is necessary to include their own clinical experience.