Process of globalization has made easier to cross borders. It has increased flow of people, traffic and goods. In Croatia, as well as in Europe and the whole world, people much easier and more often travel in search of better life, better chances for work, education, and material improvement. Globalization has positive sides because it’s the way people bring their culture and enriches society, but there are negative sides as well. Firstly, there are poorer living and working conditions of migrants that make them vulnerable and susceptible to sickness, especially to contagious diseases, which they spread to countries they travel to or to countries they return back to. One of reasons of hard working and living conditions of migrants is inadequate awareness of their vulnerability and discrimination of them according to culture, religion or race. Domicile population has difficulties in accepting foreigners and shows fear of them. Health surveillance of migrant workers should firstly be based on prevention of hard and contagious diseases, increasing awareness of benefits and importance of vaccination, by educating and informing them of possible risks they are facing and ways of avoiding their negative effects, of responsible sexual behavior and establishment of good interpersonal relationships.