Pharmaceutical care is a new modus operandi of pharmacists' work centered on the patient and his specific therapeutic needs and problems. As a health care professional who has the greatest knowledge about drugs (chemical composition, pharmacokinetics, pharmacodynamics, side effects, interactions, etc.), it is necessary that the pharmacist actively participates in detecting, preventing and solving therapeutic problems. Due to increased number of drugs in medical use and their more frequent prescribing and inappropriate use, a need for the implementation of pharmaceutical care is imperatively imposed. Nevertheless, implementation of pharmaceutical care at all levels of health care system is still not satisfactory, not only in Croatia but also in the countries that began with this practice much earlier. At the moment, the implementation of pharmaceutical care in Croatia is partly taking place in pharmacies and hospitals. However, experience suggests that the implementation of pharmaceutical care shows the greatest benefit in general practice, where the largest number of drugs is prescribed. The pharmacist's timely therapy intervention can significantly reduce the morbidity and mortality caused by the inappropriate use of drugs, which nowadays represent not only a health problem but also an economic problem. Therefore, the aim of this study was to point out the potential that pharmaceutical care has in the providing health care. The paper provide a detailed insight into the practice of implementing pharmaceutical care in outpatient treatment in several countries. The research for this work have been conducted through academic research papers published in professional journals and available for review through the following databases: Medline, PubMed and Mendeley, textbooks and other available relevant literature. Understanding the way pharmacist can successfully integrate into the team of primary health care can be a model for their implementation in our health care system. However, the integration of pharmacists into the health care team assumes the complete separation of the pharmaceutical care from the process of mere drug dispensing. This model consists of four simultaneously represented measures: the pharmacist's assessment of the patient's drug therapy; education of all health professionals in the health care team; improving cooperation of the health care team; expanding the range of pharmacy services. It has been shown in many studies that the implementation of pharmaceutical care ensures appropriate, effective and safe use of drugs, and contributes to increasing adherence of patients and improving their overall quality of life. In this way pharmaceutical care expresses it's full potential, which benefits not only the patients, but the whole health care system.