Neuroplasticity, also known as neural plasticity or brain plasticity is a process in which the human mind changes its function and structure. It is defined as the reorganization of connections, structure or function in nervous system following trauma like stroke or traumatic brain injury. These changes can be beneficial (restores function compromised because of injury), neutral (no change), or detrimental (can have pathologic implications). While it is now recognised that adult brains continue to be somewhat prone to neural plasticity, especially in relation to brain damage, this notion on neuroplasticity was thought of as most evident during a critical period running from early childhood and possible beyond puberty. We now know the brain is capable of rebuilding new synapses through forming novel neuronal circuits in response to ischemic injury. Neurodishabilitation accomplishes the reconfiguration potential of neural networks and synapses through neuroplasticity in cognition, motor skills, mood as well influences to more reliance upon promoting self healing mechanisms or behaviors. Thus, all three branches of Neurorehabilitation are related to motor therapy targeted at a concrete muscle group which is worth mastering before any neurological illness sets in susceptibility. Neural regeneration/collateral sprouting (incorporating terms such as synaptic plasticity and neurogenesis) and functional remodeling (including equipotentiality, vicariance, diaschisis), are two of the most important themes associated with mechanisms related to post-stroke recovery in neurological system.