Autistic spectrum disorder is a neurodevelopmental disorder that affects the development of social interactions, communication and motor skills, so as learning and behavior with limited interests and stereotypes. The average time to diagnose autistic spectrum disorder is at the age of three years, though the developmental deviations, characteristic for this disorder, can be noticed even at the age of 12 months. It is estimated that 1/160 children in the world are facing this disorder. Since biological marker for autistic spectrum disorder still has not been determined, diagnosis is still based on behavioral features of a child. Diagnosis of autistic spectrum disorders manifests by different family functioning, which is why other family members need to be provided with psychological assistance. The nurse's task is to timely notice deviations from early child’s development, to guide parents to multidisciplinary team professionals and to adjust interventions to basic child’s needs. The quality of health care for a child with autistic spectrum disorder depends on the severity of the symptoms, diagnosis acceptance by the family, available professional staff, and the intensity of practicing early intervention methods in everyday life. Therapy procedures in the early intervention time and later in years should be moderated related to the child's age, interests and the preferred way of communication. The parent in therapeutic procedures has the role of a "co-therapist" and is trained by expert staff to help the child in their daily activities. An open approach of healthcare professionals to the child with an autistic spectrum disorder, combined with the education of parents, teachers and the community as a whole, helps to accept the diagnosis at a higher social level.