Diabetes is metabolic disease and at the same time one of the most common chronic diseases in children. Diabetes can be classified into the following general categories: type 1 diabetes, type 2 diabetes, specific types of diabetes due to other causes and gestational diabetes mellitus. Typically symptoms of diabetes type I are polyuria, polydipsia and polyphagia. Diabetes might be diagnosed by the concentration of the glucose in the blood. By the recommendations for the adequate metabolic control, it is important to measure the concentration of glucose in the blood three to four times a day and to track amount/value of HbA1C regularly. The basis of treatment of the diabetes type I is the use of the insuline which can be used as an insulin pen or an insulin pump. All pediatric patients with diabetes type I are potentional candidates for insulin pump treatment. Very important part of the treatment of diabetes type I is including balanced diet and regular physical activity with the standard insulin therapy. Children diagnosed with diabetes type II are often overweight so first steps in treatment are lowering the body weight. Regular physical activity is recommended individually adjusted to each child. Oral antidiabetic metformin and insulin are medicines which are used in treating the diabetes type II. Treatment of the diabetes requires multidisciplinary approach; it is trying to achieve the best co-operation between parents, patient and the medical team. The basic guideline towards successful treatment should be cognition and goal to lower and slow down the occurance of chronic complications and taking the right acions in earlier life to gain better quality of life.