Aminokiselinski derivati s endiinskom premosnicom aromatskog tipa

Markušić, Maja

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master's thesis

Aminokiselinski derivati s endiinskom premosnicom aromatskog tipa

Zagreb: University of Zagreb, Faculty of Food Technology and Biotechnology, 2008. urn:nbn:hr:159:416604

Markušić, Maja

University of Zagreb
Faculty of Food Technology and Biotechnology
Department of Biochemical Engineering
Laboratory for Cell Technology, Application and Biotransformations

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APA 6th Edition

Markušić, M. (2008). Aminokiselinski derivati s endiinskom premosnicom aromatskog tipa (Master's thesis). Zagreb: University of Zagreb, Faculty of Food Technology and Biotechnology. Retrieved from https://urn.nsk.hr/urn:nbn:hr:159:416604

MLA 8th Edition

Markušić, Maja. "Aminokiselinski derivati s endiinskom premosnicom aromatskog tipa." Master's thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, 2008. https://urn.nsk.hr/urn:nbn:hr:159:416604

Chicago 17th Edition

Markušić, Maja. "Aminokiselinski derivati s endiinskom premosnicom aromatskog tipa." Master's thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, 2008. https://urn.nsk.hr/urn:nbn:hr:159:416604

Harvard

Markušić, M. (2008). 'Aminokiselinski derivati s endiinskom premosnicom aromatskog tipa', Master's thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, accessed 22 November 2024, https://urn.nsk.hr/urn:nbn:hr:159:416604

Vancouver

Markušić M. Aminokiselinski derivati s endiinskom premosnicom aromatskog tipa [Master's thesis]. Zagreb: University of Zagreb, Faculty of Food Technology and Biotechnology; 2008 [cited 2024 November 22] Available at: https://urn.nsk.hr/urn:nbn:hr:159:416604

IEEE

M. Markušić, "Aminokiselinski derivati s endiinskom premosnicom aromatskog tipa", Master's thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, Zagreb, 2008. Available at: https://urn.nsk.hr/urn:nbn:hr:159:416604

Cite this item: https://urn.nsk.hr/urn:nbn:hr:159:416604

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Metadata

Title	Aminokiselinski derivati s endiinskom premosnicom aromatskog tipa
Title (english)	Amino acid derivatives with an aromatic type of enediyne bridge
Author	Maja Markušić
Mentor	Jasna Vorkapić-Furač (mentor)
Granter	University of Zagreb Faculty of Food Technology and Biotechnology (Department of Biochemical Engineering) (Laboratory for Cell Technology, Application and Biotransformations) Zagreb
Defense date and country	2008-06-12, Croatia
Scientific / art field, discipline and subdiscipline	BIOTECHNICAL SCIENCES Biotechnology
Abstract	Endiinski antitumorski antibiotici su jedinstvena skupina spojeva koji svoju aktivnost iskazuju stvaranjem vrlo reaktivnog 1,4-didehidrobenzenskog biradikala koji pokazuje sposobnost cijepanja dvostruke DNA uzvojnice. U svrhu pronalaženja novih, jednostavnijih endiinskih struktura koje bi djelovale selektivno, u okviru ovog diplomskog rada, priređeni su endiinski derivati alanina i leucina s aromatskom premosnicom. Dobiveni simetrično, N→N, premošteni produkti {3,3'-bis[N-(2-nitrobenzensulfonil)-L-alanin etilni ester]}-1,2-di(prop-1-in-3-il)benzen (11) i {3,3'-bis[N-(2-nitrobenzensulfonil)-L-leucin etilni ester]}- 1,2-di(prop-1-in-3-il)benzen (12) su detaljno okarakterizirani 1H i 13C NMR spektroskopskom analizom.
Abstract (english)	Enediyne anticancer antibiotics are unique class of compounds which express their activity by forming highly reactive 1,4-didehydrobenzenoid diradical capable of causing the DNA double helix breakage. For the purpose of finding new, simplier enediyne structures that would react selectively, within the framework of this Graduate Thesis, enediyne derivatives of alanin and leucin with the aromatic bridge have been prepared. Simetrically, N→N, bridged products 11 and 12 comprising aromatic type of enediyne moiety were characterized by 1H i 13C NMR spectroscopic analysis in detail.
Keywords
Keywords (english)
Language	croatian
URN:NBN	urn:nbn:hr:159:416604
Study programme	Title: Biotechnology; specializations in: Biochemical-Microbiology Course: Biochemical-Microbiology Study programme type: university Study level: graduate Academic / professional title: diplomirani inženjer biotehnologije; smjer biokemijsko-mikrobiološki (diplomirani inženjer biotehnologije; smjer biokemijsko-mikrobiološki)
Type of resource	Text
File origin	Born digital
Access conditions	Access restricted to students and staff of home institution
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Repository	Repository of the Faculty of Food Technology and Biotechnology
Created on	2017-09-04 07:15:30