Objectives There are more and more herbal preparations appearing on the market which are used as an aid for body weight loss. The aim of this paper is to provide a detailed overview and systematization of clinical studies that examined the impact of herbal products on body weight in order to receive insight into recent scientific findings about their effectiveness and safety applications. Material / Patients and Methods For the purposes of this thesis, relevant electronic database „PubMed“ was searched. The search included clinical studies investigating the herbal preparations for weight loss. Selected literature has been conected to the papers that have been investigating preparations made of plant species Hoodia parviflora, H. Gordonii, Garcinia cambogia, G. mangostana, Camellia sinensis, Citrus species, and Phaseolus vulgaris, Capsicum annuum, as well as their mixtures and mixtures of other plant species for which seperate studies have not been made. Results A total of 56 clinical studies was included int his work. Thereof 21 clinical trial investigated green tea. Of those, 7 studies examined green tea in the form of dried leaves, 9 studies that examined green tea extract, and 5 studies that investigated its active component EGCG. Garcinia sp. speices whose active component is hydroxycitric acid (HCA) were examined in 3 studies in which the above mentioned active compound was investigated. Citrus herbal preparations were examined in 16 studies which were very different in terms of the investigated plant species or preparation. In those studies, grapefruit, sweet orange, bitter orange, polyphenolic citrus preparation and mixtures of the individual plant species with other substances such as vitamins, minerals and other were examined. Bean extracts were also included (4 studies found), as well as pepper and / or its active components (in 2 studies) and 10 studies that investigated mixtures of various plant species, plant extracts and their active components. Conclusion Herbal remedies for weight loss, especialy those containing green tea and citrus species showed a significant effect, however, additional well-designed studies are required to determine their effectiveness, safety and application.