Usmjerena evolucija kao metoda u dizajnu
 novih katalitičkih aktivnosti enzima

Zubčić, Ivan

prikaz prve stranice dokumenta Usmjerena evolucija kao metoda u dizajnu novih katalitičkih aktivnosti enzima

Download
PDF 722.52 KB

undergraduate thesis

Usmjerena evolucija kao metoda u dizajnu novih katalitičkih aktivnosti enzima

Zagreb: University of Zagreb, Faculty of Science, 2022. urn:nbn:hr:217:279245

Zubčić, Ivan

University of Zagreb
Faculty of Science
Department of Biology
University of Zagreb
Faculty of Science
Department of Chemistry

Cite this document

APA 6th Edition

Zubčić, I. (2022). Usmjerena evolucija kao metoda u dizajnu novih katalitičkih aktivnosti enzima (Undergraduate thesis). Zagreb: University of Zagreb, Faculty of Science; Zagreb: University of Zagreb, Faculty of Science. Retrieved from https://urn.nsk.hr/urn:nbn:hr:217:279245

MLA 8th Edition

Zubčić, Ivan. "Usmjerena evolucija kao metoda u dizajnu novih katalitičkih aktivnosti enzima." Undergraduate thesis, University of Zagreb, Faculty of Science; University of Zagreb, Faculty of Science, 2022. https://urn.nsk.hr/urn:nbn:hr:217:279245

Chicago 17th Edition

Harvard

Zubčić, I. (2022). 'Usmjerena evolucija kao metoda u dizajnu novih katalitičkih aktivnosti enzima', Undergraduate thesis, University of Zagreb, Faculty of Science; University of Zagreb, Faculty of Science, accessed 23 January 2025, https://urn.nsk.hr/urn:nbn:hr:217:279245

Vancouver

Zubčić I. Usmjerena evolucija kao metoda u dizajnu novih katalitičkih aktivnosti enzima [Undergraduate thesis]. Zagreb: University of Zagreb, Faculty of Science; Zagreb: University of Zagreb, Faculty of Science; 2022 [cited 2025 January 23] Available at: https://urn.nsk.hr/urn:nbn:hr:217:279245

IEEE

I. Zubčić, "Usmjerena evolucija kao metoda u dizajnu novih katalitičkih aktivnosti enzima", Undergraduate thesis, University of Zagreb, Faculty of Science, Zagreb; University of Zagreb, Faculty of Science, Zagreb, 2022. Available at: https://urn.nsk.hr/urn:nbn:hr:217:279245

Cite this item: https://urn.nsk.hr/urn:nbn:hr:217:279245

Please login to the repository to save this object to your list.

Metadata

Title	Usmjerena evolucija kao metoda u dizajnu novih katalitičkih aktivnosti enzima
Title (english)	Directed evolution as a method in the design of new catalytic activities of enzymes
Author	Ivan Zubčić
Mentor	Ita Gruić-Sovulj (mentor)
Granter	University of Zagreb Faculty of Science (Department of Biology) Zagreb
Granter	University of Zagreb Faculty of Science (Department of Chemistry) Zagreb
Defense date and country	2022-09-22, Croatia
Scientific / art field, discipline and subdiscipline	NATURAL SCIENCES Biology
Abstract	Usmjerena evolucija je relativno nova metoda u dizajniranju već postojećih proteina. Metoda se temelji na uvođenju promjena u slijedu nukleotida DNA koja kodira za željeni protein. Nakon uvođenja promjena u željeni slijed nukleotida, pokušava se nekom metodom selekcije ili probira identificirati protein s promjenjenim svojstvima koja mogu sezati od od afiniteta eznima prema supstratu do termostabilnosti samog proteina. Važno je konstruirati pogodan sustav za probir ili selekciju koji omogćuje pronalaženje modificiranog proteina. Usmjerena evolucija je omogućila modifikaciju proteina u vidu kataliziranja novih reakcija, kataliziranju nastanka novih kemijskih veza, sintezi određenih molekula poput biogoriva i mnogih drugih mogućnosti.
Abstract (english)	Directed evolution is a relatively new method in designing already existing proteins. The method is based on the introduction of a change in the DNA sequence that codes for the desired protein. After the DNA sequence has been altered, an attempt is made by some method of selection to try to identify a protein with changed properties ranging from the affinity of enzymes to the substrate to the thermostability of the protein itself . It is important to construct a suitable screening/selection system that allows finding the modified protein. Directed evolution has made it possible to modify proteins in a way of catalyzing new reactions, catalyzing the formation of chemical bonds, synthesizing certain molecules such as biofuels and many other possibilities.
Keywords
Keywords (english)
Language	croatian
URN:NBN	urn:nbn:hr:217:279245
Study programme	Title: Molecular Biology Study programme type: university Study level: undergraduate Academic / professional title: sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) molekularne biologije (sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) molekularne biologije)
Type of resource	Text
File origin	Born digital
Access conditions	Open access
Terms of use
Repository	Repository of the Faculty of Science
Created on	2022-10-13 10:41:54