Job satisfaction is a construct that is most often conceptualized as an affective variable that is the result of an assessment of individual business experience. The aim of this thesis is to examine to what extent the congruence between professions and professional interests is present with the participants, to examine the predictive strength of the congruence of professional interests and the requirements of occupation in anticipation of the job satisfaction and to examine whether there are any age or sex differences in relation with compliance of professions and professional differences. There were 350 participants involved in the study between 19 and 65 years of age. Professional interests were measured with the Self-Assessment of Professional Interest Questionnaire (USPI, Šverko and Babarović, 2006), while job satisfaction was measured with a Job Satisfaction Questionnaire (Gregson, 1987). The results of this study have shown that there is an overlapping of professional interests and the requirements of the working environment and that this is most important for realistic, social and artistic interests of the participants. The hierarchical regression analysis was calculated with the aim of calculating the relationship of the compliance of occupations and professional interests with the job satisfaction. Compliance of occupations and professional interests predicts job satisfaction, where overlapping professional interests with job demands and overlapping non-disclosure of professional interests are significant predictors of job satisfaction as well. However, overlapping professional interests with job demands is a somewhat stronger job satisfaction predictor. Testing sex and age differences has shown that among these groups there is no difference in the congruency of interest and occupational satisfaction.