Worldwide, there are more than 450 million people suffering from mental disorders and a significantly larger number have psychological problems. It is estimated that globaly about 151 million people suffer from depression. Socio - economic, biological and environmental factors have implications on mental health condition. It is well known that there is no health without mental health, and that state of mental healh is precondition for personal well-being as well as the owerall functioning of the community. Depression is a common mood disorder that leads to a reduction in the ability of patients to take care of themselves and perform their everyday duties . In the most severe forms, depression can lead to suicide. Nearly one million people a year commit suicide, meaning that nearly 3,000 deaths occur every day. It is calculated that for every person who has committed suicide about 20 or more people attempt suicide. The cause of depressive disorders is not fully understood yet, although it is observed that chronic stressful events cause gradual changes in the transmission of neurotransmitters and contribute to the development of depression. Furthermore, it was noted that the introverted and passivly dependent people with reduced ability to adapt to changing environment more frequently often from recurrent unipolar disorder. In general, the course of unipolar disorder is characterized by the phases of the asymptomatic periods with periods of relapses but it is known that approximately one third of patients can experience only a single episode, occuring usually above age of 50. There are also milder cases of depression, called dysthymia, characterized by symptoms of depression such as withdrawal, social distancing, tearfulness but without the presence of vegetative symptoms. The largest percentage, about 70% of psychiatric diagnoses in outpatient family medicine, concerns some of the forms of depression. The type of therapy and duration of the treatment depends on the intensity of the disorder.