The aim of this paper is to determine the pharmacists' views on the safety and efficacy of herbal preparations and the prospects for their rational issuance and use. Among the general population prevails the attitude of herbal preparations as natural and completely safe, resulting in increased growth of uncontrollable selftreatment which is not accompanied by reporting the use of herbal preparations to either a doctor or a pharmacist. Pharmacists play a key role in preventing these events through pharmacy care and counseling and rational phytotherapy. In order to determine the pharmacist's views on the safety, efficacy and rational use of herbal preparations, a survey was conducted that included 4 general and 19 specific claims that reflect the opinions of the pharmacist on the subject. There were 50 pharmacists surveyed in the city of Zagreb during March 2019. The study found that respondents had a positive attitude on herbal preparations, more specifically their safety, efficacy and health potential, and that most of them use the preparations for their own purposes. Also, pharmacists have shown an expected level of awareness of possible side effects of herbal preparations, but also the possible interactions they may have with simultaneous use with other herbal preparations or medicines. In addition, they expressed a certain perplexity regarding the quality of herbal preparations, especially in comparison with the quality of synthetic drugs. In accordance with the above, respondents believe that herbal preparations should undergo multiple tests before being placed on the market. It is encouraging to show that almost all pharmacists regularly advise patients on the correct and safe use of herbal preparations and collect a medical history that includes both medicines and herbal preparations. Similarly, almost all respondents stated that they regularly warn patients that preparations and / or medicines should not be used at the same time with certain herbal preparations due to possible interactions. It is important to note that the vast majority of respondents are interested in additional education covering the theme of herbal preparations. So, investigated pharmacists have expressed the desire to expand knowledge and competences related to this topic in order to provide quality care to patients. Namely, the pharmacist's role is of crucial importance for the herbal preparation to be properly indicated, safe and effective, at a proper dose and for an appropriate period of use. From all of the above it can be concluded that the theme of herbal preparations, whose popularity is constantly growing, is an integral and indispensable part of the corpus of knowledge of a pharmacist.