The frescoes that adorn the early Christian burial chambers of the roman Sopianae reflect the beauty and elegance, the art of craftsmanship at a high level, and the depth of meaning and symbolism behind these visual stories, which is still today partly vague and difficult to grasp. In this paper we provide a detailed description of the scenes from the Burial Chamber with a Jar, the burial chamber of the early Christian mausoleum, and the Burial Chamber of St. Peter and Paul. They represent the culmination of early Christian painting in the region. Special attention is paid to the interpretation of the frescoes of the Burial Chamber of St. Peter and Paul. Unfortunately, they are badly damaged, which resulted in different views by researchers and various readings of the themes depicted, over the last two centuries. With some interesting details that make each scene special, we look at the issue of the cult od martyrs in Sopianae, and so called "wandering artists". A brief analysis of the technical performance of the frescoes precedes the conclusion of this paper.