Mechanisms of interaction between soluble small organic molecules and/or macromolecules with inorganic crystals are of major importance for crystallization processes in nature. Among different biogenic crystals, calcium phosphates attract attention due to their role in the normal and pathological mineralization, as well as in industrial processes. Recent investigations of the influence of additives on the formation of calcium phosphates are mostly focused on protein and their building blocks, amino acids. Althought general principles of these interactions are known, the role of specific amino acids is still unclear. The aim of this research was to investigate the influence of amino acids with side chains of different properties at physiological conditions: phenylalanine (uncharged, hydrophobic), aspartic acid (negatively charged), arginine (uncharged, polar), serine (uncharged, polar) and lysine (positively charged). The progress of precipitation was followed potentiometrically, which enabled determination of induction time. Fourier transform infrared spectroscopy, powder x - ray diffraction, scanning and transmission electron microscopy were used for characterization of the precipitates. Given results show the influence of amino acids on properties of calcium phosphates. The obtain resultes show that the infuence of amino acids on calcium phosphates’ properties dependes on the charge of their side chain.